The once green and blue world turned burnt orange and brown as the upper atmosphere was ravaged by electrical storms with the broken remains of Titan society littering its surface. Even its moon was not spared, taking on a similar appearance. On a planetary scale, Titan was left eight degrees off its axis with its gravitational pull being "all over the place". Convinced that his plan could have saved his homeworld, Thanos became dedicated to wiping out half of all life in the universe so as to spare other planets from suffering the fate of his own people.
Waiting for Thanos
- "The hell happened to this planet? It's eight degrees off its axis. Its gravitational pull is all over the place."
Following his retrieval of the Space Stone, Thanos sent the Black Order to Earth with orders to bring the Time and Mind Stones to Titan. In Ebony Maw's attempt to pry the former from Doctor Strange, he was slain by Iron Man and Spider-Man. The group then seized control of Maw's Q-Ship which crash landed on Titan. After meeting half the Guardians of the Galaxy, the six agreed to work together to defeat Thanos.
Once Thanos arrived, he briefly explained his world's history to Doctor Strange before the heroes engaged him. After managing to effectively stand their ground against Thanos, the arrival of Nebula distracted Thanos enough that the Avengers, Guardians of the Galaxy, and Strange just barely managed to immobilize Thanos long enough for Mantis to subdue him with her powers before they attempted to pry off the Infinity Gauntlet. When Mantis felt that Thanos was in mourning, however, Nebula deduced that he had killed Gamora and Peter Quill attacked the Titan in a rage breaking Mantis' concentration. Having become freed from his trance, Thanos attacked the Avengers and the Guardians, knocking the Guardians down with a powerful shockwave from the Gauntlet.
Using the Power and Space Stones, Thanos ripped apart Titan's moon and sent it hurtling at his foes, effectively separating his enemies. Being the only ones to dodge the debris, Strange and Iron Man engaged Thanos individually, but Strange was briefly knocked out and Iron Man was mortally wounded, forcing Strange to barter the Time Stone in order to save Stark's life. His prize secured, Thanos departed to Wakanda to collect the Mind Stone.
As the heroes regrouped after the battle, Thanos completed the Infinity Gauntlet and used its powers to fulfill his goal. He snapped his fingers, to wipe out half the life in the universe. Of those on Titan, only Nebula and Iron Man were spared, leaving them stranded on the dead planet while the others disintegrated into nothingness.
Five years after the Snap, Doctor Strange conjured a sling ring portal from Titan to the now destroyed New Avengers Facility to help assist the Avengers in fighting Thanos alongside their allies and previously killed members. Coming through the portal was Star-Lord, Spider-Man, Drax, Mantis and Strange.
- In the comics, Thanos' homeworld is the real-life moon of Saturn named Titan, rather than a fictional planet of the same name in another solar system.