A year after a confrontation with William Rawlins, Frank Castle left New York City and decided to travel across the United States of America to find a new life for himself. Castle makes a brief stop in Michigan and attends Lola's Roadhouse to take some beer and watch Shooter Jennings' performance. At the bar, he is encountered by Amy Bendix who teases him a bit before taking a seat.
Later, Castle notices Johnny, harassing Beth Quinn as she refused to drink with him. Castle defends Quinn, while Johnny was kicked out of the bar. Impressed with Castle's chivalry, Quinn invites him to her house after her shift and Castle agrees.
Meanwhile, in Chicago, John Pilgrim interrogates Sergei Konchevsky about his business within the Russian Mafia in New York. Suddenly, Konchevsky is contacted by Bendix who informs him that Fiona and her entire crew were massacred but the pictures for those Konchevsky paid are with her. As Pilgrim was listening, Bendix arranges a meeting with Konchevsky in Lola's Roadhouse to exchange the pictures for money. Pilgrim then kills Konchevsky and orders his mercenaries to find Bendix and take her to him.
At Quinn's place, she talks with Castle about her background and her son, Rex. Castle spends the night with Quinn, revealing her his true identity and telling about his family being brutally killed. On the next morning, Quinn takes Castle to the motel where he stayed and he says that he is going to leave Michigan at night. Quinn proposes him to stay a bit longer and meet her at the bar again. Castle changes his mind and returns to the bar to spend more time with Quinn.
Taking a rest at Good Rest Motel, Bendix attends Lola's Roadhouse where she was waiting for Konchevsky only to notice a group of mercenaries, led by Marlena Olin. Trying to escape through the window in the bathroom, Bendix is approached by Olin's men who beat her. However, they are confronted by Castle who quickly takes down all enemies in front of him. Bendix convinces Castle to help her avoid the rest of enemies.
Castle emerges into a showdown with remained Olin's crew, starting a brutal bar brawl, with Ringo being killed and Quinn shot in the shoulder. Defeating all hostiles, Castle with Bendix takes wounded Quinn to his van to get her to the hospital. En route to the Ecorse Hope Hospital, Castle is followed by more mercenaries, but proceeds to kill all of them and leaves Quinn for the care of paramedics. Castle refuses to let Bendix go and drives away from the state, together with her.
Pilgrim, together with Ferrara, arrives at Lola's Roadhouse to see the aftermath of the incident in person. Pilgrim orders Ferrera to cover the event as the turf was and track down Bendix and Castle, keeping local police away from him. Looking at the footage from surveillance cameras, Pilgrim admits Castle's fighting skills and notices that he is some kind of "unleashed dog" and find him will be the tough goal.
- Jon Bernthal as Frank Castle/Punisher
- Ben Barnes as Billy Russo/Jigsaw
- Amber Rose Revah as Dinah Madani
- Josh Stewart as John Pilgrim
- Giorgia Whigham as Amy Bendix
- Alexa Davalos as Beth Quinn
- Jagger Nelson as Rex Quinn
- Teri Reeves as Marlena Olin
- Michael Pemberton as Lieutenant Ferrara
- Alex Notkin as Sergei Konchevsky
- Avery Mason as Ringo
- Peter Albrink as Johnny
- Adrian Alvarado as Eddie
- Lucas Kane as Drunk
- Daniel Tirado as Paramedic
- Kym Gomes as Maid
- Ian Poake as Tech
- Lenny Thomas as Customer
- Khalil' La'Marr Pickett as Operator
- Kiera O'Connor as Woman in Bar
- Shooter Jennings as Himself
- Theo A. Kamp as Himself
- James Douglass as Himself
- John F. Schreffler, Jr. as Himself
- Aubrey Richmond as Herself
- Mark Richard Goldman as Bar Patron (uncredited)
- John Donchak as Bar Patron (uncredited)
- Jay Kwon as Thug (uncredited)
- Unknown Actor as Officer Olsky (uncredited)
- Chicago, Illinois
- New York City, New York
- Assassination of Sergei Konchevsky
- Chase of Amy Bendix
- Duel at the Central Park Carousel (flashback)
- Massacre in Chicago (mentioned)
- Massacre at Central Park (mentioned)
- United States Department of Homeland Security
- Marlena Olin's Crew
- Russian Mafia
- New York City Department of Correction
- Fiona's Crew (mentioned)
- United States Marine Corps (mentioned)
- New York Rangers (mentioned)
|The Outsider||Shooter Jennings, Theo A. Kamp, James Douglass, John F. Schreffler, Jr. and Aubrey Richmond|
|Outlaw You||Shooter Jennings, Theo A. Kamp, James Douglass, John F. Schreffler, Jr. and Aubrey Richmond|
|Wild & Lonesome||Shooter Jennings, Theo A. Kamp, James Douglass, John F. Schreffler, Jr. and Aubrey Richmond|
|The Other Life||Shooter Jennings, Theo A. Kamp, James Douglass, John F. Schreffler, Jr. and Aubrey Richmond|
|The Real Me||Shooter Jennings, Theo A. Kamp, James Douglass, John F. Schreffler, Jr. and Aubrey Richmond|
|Me and Bobby McGee|
(Roger Miller cover)