- "You guys know what to do."
- ―Melinda May
The New Director
With S.H.I.E.L.D. signing the Sokovia Accords, Jeffrey Mace replaced Phil Coulson as the leader of the organization. As part of his moves to separate Coulson's former inner circle, Mace assigned Melinda May the task of creating, training and leading a specialist STRIKE team. May recruited Piper and several more agents to her team. One Day, May trained her team in martial arts in the Playground hangar. After she defeated her opponent, May asked her team why he failed. One of her Agents said the opponent had not seen her back kick, but Piper corrected, answering that he tapped out. Zephyr One then landed and May asked Piper to train them for her. Jemma Simmons and Leo Fitz created for the team some gadgets, including Framework for their training and Mapping-Action Eyewear for battles.
Later, Simmons discovered that May helped Coulson and Alphonso Mackenzie finding Daisy Johnson, despite Mace's disapproval. She ordered May and her team to bring the two back and clean up their mess. The team arrived to Los Angeles and May shared the image of the building Coulson and Mackenzie were watching. With I.C.E.R.s, the team took out all of the Chinatown Crew members and took a mysterious box from the scene.
Melinda May informed Piper to get the team ready for training. However, Phil Coulson prepared the team without May's knowledge to restrain her, since she acted strangely. After Coulson brought May to the room, May suspected something was wrong and started fighting her team members. Coulson urged them not to hurt her, but May beat all of them. Surprisingly, director Jeffrey Mace came to the room and managed to knock her out, revealing he was an Inhuman.
As Melinda May and Phil Coulson needed help to get out from South Ridge Penitentiary, Alphonso Mackenzie sent Daisy Johnson to led Prince and Davis to find May and Coulson. Prince and Davis used I.C.E.R.s to fight their way to the two.
Chasing a Ghost
Melinda May and members of her team came to Momentum Labs in order to find Lucy Bauer and Eli Morrow. However, Bauer had already left the place. All May and her team found were corpses of S.H.I.E.L.D. agents who were assigned to guard the place. Later, Leo Fitz located Bauer and Morrow in an old Roxxon Corporation powerhouse. May's Team met Phil Coulson, Fitz, Alphonso Mackenzie and Robbie Reyes there. The team split to find the ghost. Mackenzie then ordered the team to get back to the Quinjet and help him carry an EMP device. As they returned, an Coulson, Fitz and Reyes were caught in an explosion. The team and Mackenzie rushed to find them. The team found Morrow walking in the hallway and asked him to come with them. Morrow used his powers to kill the agents with carbointed sharps and escaped.
Chasing the Watchdogs
|Melinda May||Level Red||Melinda May is an elite S.H.I.E.L.D. agent, and one of the agency's veteran field operatives. A close friend of the former Director Phil Coulson, May was ordered by new Director Jeffrey Mace to lead the strike team. Although she does not trust Mace, May assembled the team. For a time, she was incapacitated since her mind was infected by Lucy Bauer, driving her insane; Mace himself was forced to subdue her. However, she was later cured by Jemma Simmons and Holden Radcliffe.|
|Piper||Level Red||Piper was one of the agents in Director Coulson's Tactical division, having previously been chosen as one of the field operatives to attack Hive on Union City. She went on to continue working under Melinda May's direct orders as a field operative on her team. She also received training in order to become the team's field medic.|
|Davis||Level Blue||Davis was a S.H.I.E.L.D. Agent, working for them before the HYDRA Uprising and returning to the Agency once Jeffrey Mace took over as Director and S.H.I.E.L.D. was reestablished following the signing of the Sokovia Accords which Davis supported. Davis learned to pilot the Zephyr One to serve as a pilot for the team.|
|Prince||Unknown||Prince was recruited into working under Melinda May's direct orders as a field operative on her team.|
- Robbie Reyes/Ghost Rider
- Chinatown Crew
- Chen †
- Lucy Bauer †
- Eli Morrow †
- Life-Model Decoys
In chronological order:
- Agents of S.H.I.E.L.D.