Lagos is the largest city of Nigeria.
Rumlow traveled to Lagos and planned to steal a biological weapon from the Institute for Infectious Diseases. However, Captain America became aware of the planned attack and informed the other Avengers.
After noticing an incoming garbage truck was quickly approaching the IFID, Falcon deployed the Redwing only to realize the truck was a battering ram.
By then, however, the "truck" had driven through the entrance and Rumlow's mercenaries had opened fire on several security guards. As poisonous gas slowly flooded the building, Rumlow quietly made his way to the third floor and found the bioweapon he was looking for.
The Avengers then converged on the building and proceeded to take out several of the mercenaries. Falcon used the Redwing to find and confirm Rumlow's location before informing Captain America.
Using her powers to lift Captain America onto the third floor, Scarlet Witch then focused on venting the gas out into the open air while the others proceeded to deal with the remaining mercenaries.
Captain America searched for Rumlow only to learn that he had already left. Black Widow managed to intercept Rumlow and tried to electrocute him only to learn he can no longer feel pain.
He then threw a grenade at her, but she used a dead mercenary's body to shield herself from the blast. Rumlow escaped, but not before entrusting the bioweapon to one of his men.
While Falcon, Scarlet Witch, and Black Widow set out to retrieve the bioweapon, Captain America confronted Rumlow and learned that the former STRIKE commander blamed him for his injuries.
Meanwhile, Black Widow managed to locate the bioweapon and confronted the mercenaries tasked with maintaining it. When they threatened to kill everyone in the surrounding area unless she surrendered, she reluctantly complied. The Redwing suddenly appeared and subdued them while Black Widow secured the bioweapon.
Captain America managed to subdue Rumlow and began pressing him for information as to the identity of the person who ordered him to obtain the bioweapon. Rumlow claimed Bucky Barnes was pulling the string before activating a suicide bomb attached to his vest, intentng on taking Captain America with him.
Scarlet Witch managed to contain the explosion around Rumlow and tried to move the blast away from innocent bystanders. However, she moved it too close to a nearby building and inadvertantly destroyed it, killing numerous civilians and 11 relief aid workers from Wakanda.