- Justin Theroux previously wrote the script for the film Tropic Thunder, starring Robert Downey, Jr., who recommend Theroux to Jon Favreau in order to write the screenplay for Iron Man 2.
- Justin Theroux previously worked with Eugene Lazarev in Duplex.
- Justin Theroux worked again with Sam Rockwell in Mute.
- Justin Theroux was considered for the role of Doctor Strange in Doctor Strange.
- Justin Theroux portrayed Ethan Chase in the DC Entertainment production Joker.
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