- James Marsters also voiced Sergei in Spider-Man: The New Animated Series.
- James Marsters also voiced Korvac and Chitauri #3 in Ultimate Spider-Man.
- James Marsters also voiced Reed Richards/Mister Fantastic in The Super Hero Squad Show.
- James Marsters is one of the actors to portray characters for both Marvel Studios and DC Entertainment. He portrayed Brainiac in Smallville and voiced Lex Luthor in Superman: Doomsday and DC Universe Online.
- James Marsters shares his birthday with Ben Barnes.