- "Excellent. Please tell your wife she makes it even better than they did in Constantinople."
"I think you mean Istanbul, ma'am. Constantinople, that is its ancient name."
- ―Alexandra Reid and Kadir
Istanbul, formerly known as Constantinople, is the largest city in Turkey.
- "How was the drive from Istanbul?"
Centuries ago, one of the leaders of the Hand visited the city of Constantinople.
Istanbul was the word chosen as part of the sign used by the security protocol of the Guest House to allow entrance to the people that approached the compound.
Istanbul was one of the cities where was located Hand's trade route for Steel Serpent's sale using the Rand Enterprises' resources.