Hydra Super-Serum

For the real-life version of the Hydra Super-Serum, see Calvin Zabo's Formula

"He discovered that there were universes stacked on top of his own..."

The subject of this article comes from an alternate universe connecting to the main timeline of the Marvel Cinematic Universe. This universe is designated as the "Framework".

"The point is... One dose, you will have the Patriot begging for his life."

The Hydra Super-Serum was an alternate version of Calvin Zabo's Formula used by Hydra inside the Framework.

History[]

"You've got about an hour of augmented strength. Don't waste it."

In an attempt to defeat the Patriot, Hydra scientist Kenneth Turgeon created a serum that would temporarily enhance the user's strength. After seeing it for herself, Melinda May allowed The Doctor to inject her with the serum before taking off to face the Patriot at the Hydra Enlightenment Cultivation Center.

May initially proved to be a challenge for the Inhuman Resistance leader, but was defeated when the serum's effects started to wear off.^[1]

Like everything else in the Framework, the serum was deleted when Aida shut down the simulation.^[2]

Several of the ingredients – more specifically, the various metabolic enhancers, the gorilla testosterone and the drop of peppermint – are the same ingredients Jemma Simmons found while analyzing Calvin Zabo's Formula.^[3]