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Designed by Rocket Raccoon out of the spare parts of the Milano, the Hadron Enforcer was used against Ronan the Accuser and the Cosmi-Rod in the Battle of Xandar. It was also used to threaten the Ravagers when they held Peter Quill and Gamora captive.
When Star-Lord and Gamora were captured by the Ravagers, Rocket Raccoon and Drax the Destroyer threatened to use the Hadron Enforcer to destroy the Eclector. Star-Lord was able to make a deal with Yondu Udonta and radio Rocket to back down.
During the Battle of Xandar, Star-Lord used the Hadron Enforcer on Ronan the Accuser, but it proved ineffective, the Kree warlord taking it to the chest with barely any sign of damage. When the Dark Aster crashed on Xandar, Quill supplied a distraction in the form of a dance-off, giving Rocket Raccoon enough time to repair the weapon, after which Drax used the gun to destroy the Cosmi-Rod and release the Power Stone.
The Hadron Enforcer is a weapon that can fire a bullet that contains hadron particles, which explode on impact of the target. Depending on the amount of matter and mass the target has the shell blast can, per Rocket's prerogative, shatter lunar bodies.