Your name is Natalie isn't it
"Your name is Natalie, isn't it?"
The title of this article is conjectural. Although this article is based on canonical information, the actual name of this subject does not

coincide with the information represented, and a new name has been or has to be proposed for the article. Please see the relevant discussion for the name on the talk page.

"You know I don't like needles."
"Well, I mean, it's a bee sting, really."
Alphonso Mackenzie and Leo Fitz[src]

The Ghost Infection Antidote is an antidote created by Leo Fitz and Jemma Simmons in response to the threat of Lucy Bauer and her team who could infect people with a lethal disease.


"If we're gonna track her down, we're gonna need that antidote. Fitz said that they were close."
"I don't want it close. I want it here."
Alphonso Mackenzie and Phil Coulson[src]

Upon being released, Lucy Bauer infected Chen and later Melinda May. They suffered from a lethal disease which made them see other people with demonic faces, keeping them in a state of constant terror. Eventually, Chen died because of the disease and May almost did but was saved by Jemma Simmons and Holden Radcliffe. While curing May, Simmons and Radcliffe scanned her brain, which enabled them to understand the mechanism of the infection.[1]

Fitz Ghost Antidote

Leo Fitz demonstrates how the Antidote must be injected

Simmons and Leo Fitz used the data of May's brain scan to create the antidote as a means to fight against Bauer and her fellow scientists. They managed to create it in time before S.H.I.E.L.D. went to the South Ridge Penitentiary to rescue Phil Coulson and Melinda May who were trapped with a prison staff infected by Bauer. Fitz provided the team with several syringes, explaining how it worked.

Mack Ghost Antidote

Alphonso Mackenzie injects himself with the Antidote

Quake, Davis and Prince found Coulson and May in the Penitentiary and injected the antidote to Warden Green and his officer. Meanwhile, Alphonso Mackenzie was infected by Hugo, but injected himself with the antidote before he could suffer from the disease.[2]


"So, these work like EpiPens?"
"Almost, but more efficient. To counteract the psychosis, the serum needs to be delivered directly into the brain stem, so the injector needs to be placed at the base of the skull."
Davis and Leo Fitz[src]

When activated, the syringe displays four little stings which go through the patient's skin to deliver the Ghost Infection Antidote in the organism. The antidote directly counters the effects of the disease induced by the ghosts' touch and acts with immediate effects. However, the injection causes pain to the patient as the antidote must be injected directly in the brain stem, meaning that the needle must be put right above the neck at the base of the patient's skull.


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