John Garrett and Antoine Triplett are attacked by Mike Peterson, who had been reborn as Deathlok, at a S.H.I.E.L.D. safehouse. Several weeks later, they along with Victoria Hand, Jasper Sitwell and Felix Blake join Coulson's Team in their hunt for the Clairvoyant.
The agents split into teams to pursue leads on different Clairvoyant candidates. At a nursing home searching for Thomas Nash, a catatonic man who once claimed to be a psychic, Melinda May and Blake encounter Deathlok. Before critically injuring Blake and escaping, he claims that "Mike Peterson is dead" upon being reminded of his son.
However, Blake manages to tag Peterson with a tracker before he fled. Concluding that Nash is the Clairvoyant because of Deathlok's presence, along with the falsifying of his nursing home records, the team converges on Deathlok's next location, an abandoned horse racing track, while Triplett and Jemma Simmons stay behind at the Hub with Hand.
The team briefly encounters Deathlok again, but he flees into the sewers. They discover a hidden room where Thomas Nash, a vegetative man on life support who could only speak through a computer, is hiding. Nash surrenders and boasts that as the Clairvoyant, he would always be watching them. When he says that the Centipede Project would kill Skye, Grant Ward instantly shot him dead.
Meanwhile, Leo Fitz attempts to create a secret phone line so that he could speak to Simmons from the Bus. While there, he discovers a bug that leads him to May's secure line. Phil Coulson realizes that Thomas Nash is not the Clairvoyant. When Skye presents the results of her studies on the S.H.I.E.L.D. psychological files of the potential Clairvoyants, they realize that the Clairvoyant is a member of S.H.I.E.L.D., with access to the same files. This gives the Clairvoyant knowledge of how to manipulate the agents.
Coulson accuses the detained Ward of working with the Clairvoyant and shooting Nash to direct them away from the Clairvoyant's true identity. They are interrupted by Skye, who had learned of May's unapproved phone line from Fitz. Coulson and Skye end up in a standoff with May in the Bus's hangar. As May tries to explain that she was not allowed to identify to whom the line went, control of the Bus is hijacked.
At the Hub, Hand orders that everyone aboard is killed, except for Coulson, claiming, "He's mine."
- Clark Gregg as Phil Coulson
- Ming-Na Wen as Melinda May
- Brett Dalton as Grant Ward
- Chloe Bennet as Skye
- Iain De Caestecker as Leo Fitz
- Elizabeth Henstridge as Jemma Simmons
- Bill Paxton as Agent John Garrett
- Saffron Burrows as Agent Victoria Hand
- J. August Richards as Michael Peterson/Deathlok
- B.J. Britt as Agent Antoine Triplett
- Titus Welliver as Agent Felix Blake
- Maximiliano Hernández as Agent Jasper Sitwell
- Brad Dourif as Thomas Nash
- Sydney, Australia
- Milton Keynes, England
- Macon, Georgia
- Muncie, Indiana
- Ball State University (mentioned)
- Pensacola, Florida
- Hub, Alaska
- Phuket, Thailand (mentioned)
- Cairo, Egypt (mentioned)
- Bora Bora, French Polynesia (mentioned)
- Canada (mentioned)
- S.H.I.E.L.D. Headquarters (mentioned)
- Washington, D.C. (mentioned)
- Triskelion (mentioned)
- Fridge (mentioned)
- Ian Quinn's Villa (mentioned)
- North Pole (mentioned)
- Centipede Device
- Backscatter X-Ray Eye Implant
- Cybertek Prosthetic Leg
- Forearm Rocket Launcher
- Tag Rounds
- Medical Pod
- Bulletproof Vest
- Golden Retrievers
- S.H.I.E.L.D. Satellite
- Taser Projectile Launcher
- GH.325 (mentioned)
- Tracker (mentioned)
- Monkeys (mentioned)
- British Armed Forces (mentioned)
- Yakuza (mentioned)
- Department H (mentioned)
- Dan Monroe
- Elijah Fordham
- Noriko Sato
- Ace Peterson
- Edison Po
- Ian Quinn
- Nick Fury
- Robert Coulson
- Dan Monroe's Son
- Santa Claus
- John Watson
- Kennedy family
- The X-Ray shot of Deathlok in this episode is a reference to his comic book appearance, where his facial implants are clearly visible, and he no longer has a nose, eyebrows, or lips (due to being a reanimated corpse).
- Jasper Sitwell is sent to the Lemurian Star during this episode. During the first action sequence of Captain America: The Winter Soldier, Agent Sitwell is one of the hostages on-board the ship. This places the start of the film's events around just after this scene.
- This episode does not feature an after-credits scene. Instead, footage from Captain America: The Winter Soldier was shown.