The Ecorse Hope Hospital is the hospital located in the state of Michigan.
Following the bar brawl at the Lola's Roadhouse, Beth Quinn was heavily wounded by Marlena Olin's mercenaries. Frank Castle and Amy Bendix took wounded Quinn to Castle's van and took her to the nearest hospital. As Castle took down the last mercenaries after them, they finally got Quinn to Ecorse Hope Hospital. As the paramedics wheeled her away, she begged Castle to go to avoid trouble with the police.
Quinn was recovering at the hospital, but upon awakening she saw John Pilgrim at her bedside, reading over the many get well cards her loved ones had left for her, particularly the one by her son. As they conversed, Pilgrim asked for Castle's identity, threatening her son's life if she did not answer. Terrified Quinn revealed his assumed name: "Pete Castiglione." Pilgrim promised to offer a prayer for her recovery before departing.