Once he had assumed the role of King of Wakanda, Erik Killmonger ordered the delivery of Vibranium weapons to War Dog operatives around the world. Members of the Border Tribe loaded large amounts of weapons on the Dragon Flyers. However, the first Flyer was shot down by Black Panther, who attempted to stop Killmonger. Killmonger then ordered the rest of the loaded aircraft to take off. While most of them headed to the border, several aircraft remained to assist the Border Tribe. When one of them fired at T'Challa, he took a Sonic Spear and used it to take the Flyer down.
Shuri then asked Everett Ross to remotely take control over the Royal Talon Fighter to destroy the Dragon Flyers before they could reach the border. Ross managed to take down several aircraft before the rest turned around and then began firing back at him. This forced Ross to avoid their shots as best he could while still trying to shoot them out of the sky.
However, another Dragon Flyer had begun to fire at Ross in Shuri's lab. Although Shuri ordered Ross to get out while he still could, Griot confirmed that the glass was only fifty percent damaged, although the Flyer was still shooting. Defiant, Ross decided that he would continue with his mission, regardless of the immediate danger before him. Ross then pursued the last Flyer loaded with Vibranium which headed to the border while the two remaining Dragon Flyers used electric hooks to stop him. On Shuri's advice, Ross destroyed them using a sonic overload. Ross then destroyed the last Dragon Flyer by ramming it with the Royal Talon Fighter and escaped from the lab before Flyer destroyed the lab.
Multiple Dragon Flyers were used by Wakandans to fight against Black Order and Outriders. Together with Thor, Flyers attacked the Outrider Dropships. Unfortunately, when Thanos gained all the Infinity Stones and enacted his Snap, several Flyers violently crashed on the battlefield as their pilots were disintegrated.