Charles Murphy is an alumnus at the Midtown School of Science and Technology, and a former member of the school's decathlon team.
- "What is the heaviest naturally-occurring element?"
"Hydrogen's the lightest. That's not the question. Okay."
- ―Liz Toomes and Charles Murphy
Murphy was a member of the Midtown School of Science and Technology's Academic Decathlon Team. As such, he took part in rehearsals before the nationals, although he had a tendency to give unrelated answers to questions.
Trip to D.C.
- "We're freakin' screwed!"
- ―Charles Murphy
Murphy joined the rest of his team for the Academic Decathlon's nationals in Washington, D.C., expressing amazement at the hotel they were staying in. The night before the nationals, Murphy went to the hotel's swimming pool with the other students.
The day after, Murphy went to the nationals with his team. Despite Peter Parker's absence, they were victorious. As a reward, Roger Harrington took his students, including Murphy, to the Washington Monument. However, while they were in the elevator, the Chitauri Energy Core in Ned Leeds' backpack released an energy pulse, damaging the elevator. Although Murphy was convinced they would die, he and the other students were successfully rescued by Spider-Man.
Back to Midtown
- "It was tight, like a Bon Jovi concert!"
- ―Charles Murphy
Murphy safely returned to Midtown School of Science and Technology where he was interviewed for the school TV channel and displayed quite an enthusiasm while describing what had happened. Following the homecoming party, Murphy and the rest of the team were congratulated by Roger Harrington for their victory and applauded as Michelle Jones was appointed the new head of the team.
- Midtown School of Science and Technology
- Monica Warren - Former Teacher
- Roger Harrington - Former Teacher
- Liz Toomes - Former Classmate and Decathlon Leader
- Ned Leeds - Former Classmate
- Peter Parker - Former Classmate
- Michelle Jones - Former Classmate and Decathlon Leader
- Flash Thompson - Former Classmate
- Sally Avril - Former Classmate
- Cindy Moon - Former Classmate
- Abe Brown - Former Classmate
- Betty Brant - Former Classmate
- Tiny McKeever - Former Classmate
- Seymour O'Reilly - Former Classmate
- Jason Ionello - Former Classmate
- Spider-Man - Savior
- In the comics, Charles Murphy was one of Peter Parker's childhood friend who joined Flash Thompson's group during high school.
- Charles Murphy is a fan of Bon Jovi.