- "I'm living out the rest of my life on my terms."
- ―Agnes Kitsworth
Agnes Kitsworth was an art collector and Holden Radcliffe's former romantic interest. After he left her to find a cure for her brain tumor, Radcliffe used Kitsworth's semblances to create a body for his assistant Aida while she went to live out her days in peace. Eventually, Kitsworth was approached by S.H.I.E.L.D. who were attempting to arrest Radcliffe, but Kitsworth instead sided with her ex-partner and allowed him to log her into the Framework, where her mind could live in peace while her body died. Despite living with Radcliffe in the virtual world for a time, Kitsworth was confronted by HYDRA and Leo Fitz, who executed Kitsworth when Madame Hydra convinced Fitz that Kitsworth was a clone.
Relationship with Holden Radcliffe
Kitsworth met scientist Holden Radcliffe and the two started to date. At this occasion, Radcliffe shared his transhumanist views with his girlfriend. When Kitsworth was diagnosed with a glioblastoma multiform, a form of brain cancer that had formed tumors in an inoperable part of her brain, Radcliffe tried everything he could in order to cure her. However, each of his attempts failed, making him leave Kitsworth.
After Kitsworth and Radcliffe separated, Kitsworth decided to abandon her old life in order to live the few remaining years that she had left at her own will and went to a place where no one would say they are sorry by learning of her disease.
Kitsworth told Coulson and Mackenzie of her relationship with Radcliffe and how they had broken up after Kitsworth was diagnosed with cancer, chastising Mackenzie for saying that he was sorry for her as she did not want to hear that anymore. Coulson tried to convince her to help them but Kitsworth bluntly rebuked him, saying that she did not want to have anything to do with Radcliffe anymore.
Kitsworth returned to her apartment where she was soon visited by Coulson, who apologized for his behavior on their first meeting. Coulson told Kitsworth the story of his dear friend May who had been captured by Radcliffe and replaced by an android. Although she was doubtful about Radcliffe's alleged ill actions, Kitsworth was affected by what Coulson had told her and agreed to help S.H.I.E.L.D. find Radcliffe.
Reunion with Radcliffe
- "Come with me, Agnes, please. I can save you. You can live."
- ―Holden Radcliffe to Agnes Kitsworth
Radcliffe gave instructions to Kitsworth so that the two could meet. Kitsworth finally found her ex-boyfriend who told her about the Framework, an alternate reality he had designed and in which Kitsworth could live without fearing death. After hesitating, Kitsworth agreed to follow him, keeping S.H.I.E.L.D. from arresting him.
Holden Radcliffe took Kitsworth to the Ivanov Oil Platform, where the Framework hardware was located. Radcliffe and Aida then connected Kitsworth's body to the Framework. Her consciousness was successfully uploaded in the alternate reality and shortly after, Radcliffe euthanized her body and Aida took her necklace for herself.
According to Radcliffe, Kitsworth's body was given a proper and emotional burial at the sea.
Death In The Framework
In the Framework, Kitsworth began living a peaceful life in a beautiful residence located on an island named Ogygia where she was soon joined by Radcliffe himself, since his own body had been murdered by Aida and his consciousness uploaded in the Framework as well.
Kitsworth was found by The Doctor, who could not help but notice her extreme resemblance with Madame Hydra and executed her after he was convinced that she was a simple copy. Therefore, Kitsworth's consciousness was permanently destroyed.
- "I wake up and face death everyday. You think I'm scared of you?"
- ―Agnes Kitsworth to Phil Coulson
In the Framework
- Ogygia: In the Framework, Kitsworth resided with Holden Radcliffe on the island of Ogygia, where she had a peaceful life. However, she was ultimately captured by HYDRA operatives looking for S.H.I.E.L.D. agents on the island and was murdered by The Doctor in front of Radcliffe.
- Holden Radcliffe † - Love Interest and Euthanizer
In chronological order:
- Agents of S.H.I.E.L.D.