I know this is probably an unorthodox choice but I have been binging Runaways on Disney+ and I have officially got a new most hated villain in the MCU. Kilgrave is despicable and he deserves everything that happens to him in Jessica Jones season 1 but if I might say screw Leslie Dean.
She is an opportunistic villain who directly organizes the PRIDE as a cult that murdered 15 children, framed their own children for the death of the latest sacrifice to Jonah, she caused the deaths of both Molly's bio-parents who were also members of PRIDE until they discovered that their plan was going to destroy the world and brainwashed her own husband out of PRIDE because she didn't think he had the stomach to do what she did while she had an affair with Jonah even if it purely Jonah needing an heir and nothing romantic she clearly was romantically attracted to him.
Karolina's entire life was devoted to the church that her mother ran and she has to now tackle the fact that her religion, something that clearly brings her comfort was created in the name of all this. Other members of PRIDE, mainly Alex and Nico's fathers and especially Gert and Molly's parents feel genuine compassion for their children and remorse for what they do even if they don't know how to get out of PRIDE but Leslie doesn't seem to care about Karolina at all