I originally didn't know who she was, so I searched her up and discovered that she was Madame Hydra in the comics.
Admittedly, I was a bit saddened because I'm a huge fan of Agents of SHIELD and I loved AIDA/Ophelia's version of Madame Hydra. However, this did take place in the Framework, so it's possible that Madame Hydra could reappear in the MCU in a different form.
Thoughts?