Yes

Matt Murdock and Claire Temple

Friendship: Yelena and Bob (Really Yelena and most of the Thunderbolts* except for Bucky lol), I want to say 616 Yelena and Kate Bishop but I'm about 99% they are friends in the comics as well lol.

Romantic: Laura and Clint Barton.

Star-Lord and Gamora, they were really interesting as a couple. Prior to the MCU adaptation, Gamora was with Nova and Star-Lord hecking died

@IronWidowMaikuB why except for Bucky?

Because they are sorta kinda a thing now in the comics. Comics Yelena and Bucky has slowly but surely become friends in the comics and partners due to how the comics told the Black Widows and Bucky story.

Now granted he ain't as close to her as he is to say The OG Natasha and even CloneNat, but it's not like say Walker and Yelena in the comics where they have like zero friendship and barely knows each other even though they were at one point on the same team.

@LardWad420 I really enjoyed Star-Lord and Gamora's arc. It was said to see her go, but I'm really happy with James Gunn's decision to not have CTH Gamora start a relationship with Peter. They're two different people with two different histories, and he respected that.

I liked the relationship between Black Panther and Nakia since it reminded me a lot of the relationship between him and Storm. Something we may sadly never get in this franchise.

Iirc, Nakia was a villain in the comics who had unrequited feeling for T'Challa.

I guess FitzSimmons since they didn't originate in the comics, even if they were integrated afterwards.