So, I thought I had this whole thing figured out, but then two things threw me for a loop. One was Miguel saying "polimultiverse", the other was Loki becoming ruler of the multiverse, because, while epic, that leaves a lot of questions regarding the Council of Kangs. Here's how I think it is:
The Sacred Timeline (Earth-870) was never alone, just isolated.
The Spider-Society exist at the same time as the TVA, policing the polimultiverse.
He Who Remains invented Canon Events as a way to avoid Evil Kang Variants in the polimultiverse.
He destroyed the universe where Miguel's daughter lived (Earth-1042) because according to his algorithm, it would result in an evil version of himself.
LYLA is a copy of Miss Minutes.
The Council of Kangs is in the void.
In terms of Multiverse vs Polimultiverse, the MULTIVERSE is the sacred timeline and its branches, including all live action marvel content+ What If...?, and the POLIMULTIVERSE is all other animated, video game, and comic-book content, and existed before the events of Loki.
Any questions?