I think Bruce is retired from physical acting so it would have been cool, but not practical.

That’s unfortunate.

Chris McKenna has said that such Mysterio was gonna be a variant of the MCU one, so Jake Gyllenhaal was meant to return.

Ok, but it would have been cooler if they were able to do Bruce Campbell Mysterio

Yeah, but people who haven't research about Spider-Man 4 wouldn't have gotten the reference, plus it was Tom Holland's movie and not Tobye Maguire's as much as it hurts to admit. XD

Yeah, it really isn’t needed, but since Raimi was never able to imply that in Dr Strange 2 for obvious reasons, it would have been a cute bonus reward.

I mean if Bruce did played Mysterio it wouldn't have been a big role.

Vulture would have been better because he was supposed to be in the movie

Yeah, would have been like Sandman or the Lizard