A very heartbreaking, yet inevitable fact, was first reported on Reddit by GreenGengar459. As this user suggests, the first scene after the five-year gap sees Steve Rogers managing a support group for those who seek to move on from everything they lost from the snap. What is most surprising, though, is the Captain's mention of the Mad Titan indicating that those present know who Thanos is and what he did.
This means that at some point during those five years, the Avengers had to inform the worldwide public that some giant purple alien used a bunch of magic rocks to erase half of the planet's population. Having to make that sort of announcement must have been one of the, if not the hardest things, Earth's Mightiest Heroes had to do during that period of time. Hearing that all hope is lost from the Avengers themselves must have been equally as heartbreaking for the public.