@Andrew Ronning I personally don’t think Secret Invasion would be the way to go regardless. As @BEJT mentioned, the implications of the event would undo a lot of character development in a rather cheap way.
Additionally, the Secret Invasion comic featured:
1) An army of Super-Skrulls as their main fighting force (which would be hard to pull off in the MCU visually, especially since there are much fewer heroes in the MCU than in the comics).
2) The Skrulls were motivated by religious extremism (which would probably be in in bad taste on screen).
Basically, you would have the throwaway the main elements of what made Secret Empire cool, and you’re left with a race of generic warmongering aliens, no different than the Chitauri (only now they have the potential to lazily undo character development).
I would much rather them focus their efforts on something else, especially considering Secret Invasion wasn’t that great of a comic to begin with.