I’d say Dr. Strange is the most enlightened, as he has knowledge of the secrets of the multiverse due to his role as Sorcerer Supreme.

But in terms of raw intellect, probably Shuri.

I’d disagree, Marvelus. Tony Stark was born to a billionaire genius who had access to some of the most advanced technology on the planet. To bring upbringing into the equation feels moot.

Even if we ignore how young Shuri is comparatively, she has demonstrated she can readily comprehend foreign concepts (like Vision’s operating matrix) as quickly as Stark and Banner.

Having access to advanced technology isn’t what makes Shuri the smartest, but her capacity to creatively adapt that technology in a way that no one else seemed able to do.

It’s more about aptitude than accomplishment.