Board Thread:Questions and Answers/@comment-1894786-20161016014021/@comment-29908830-20170311081426

SonOfAres1 wrote: I think there will be brief references to the Avengers and such, but the show will be very isolated to the rest of the universe if it's in the MCU.

That's pretty much what it will be. The Netflix shows do that, so Hulu will probably do the same.