Karen

"Karen, target all the structure points!" "Peter, you have been 98% successful."

- Spider-Man and Karen

Karen (also known as K.A.R.E.N.) is a natural-language user interface created by Tony Stark, designed to work alongside and aid Spider-Man in his crime-fighting duties.

Queens' Colorful Local Crimestopper
"Good evening, Peter." "Hello?" "You have 576 web-shooter combinations."

- Karen

After Peter Parker was allowed to keep the Spider-Man Suit, he began to frequently use the suit after school and became known as "Queens' Colorful Local Crimestopper", a name given to him by the media. During one of his excursions, the Karen A.I. was activated, much to his surprise, and she alerted him that he had many different web shooter combinations available to use as well as granting him a heads-up display view through his eye lenses.

Bombing of the Washington Monument
"I got you." "This your chance, Peter. Kiss her."

- Spider-Man and Karen

To be added

Attack on the Staten Island Ferry
To be added

Allies

 * Tony Stark/Iron Man - Creator
 * Peter Parker/Spider-Man - Primary User