Board Thread:Questions and Answers/@comment-7657843-20150504102237/@comment-26281196-20151204135457

All the Stones can generate energy. Red Skull used it power without knowing how, this activated a strange effect who teleported him. Then, the Tesseract overheats and melts the floor

It's impossible to say that, if the user teleports without a location, the Tesseract would send him into the space or randomly teleport or even if it works without one. No one considered explaining how the teleportation worked so we only know it teleports :)

In the case of the Red Skull, the teleportation have two possibilities: He was trying to escape and knew where he was going. He was trying to escape and didn't knew. We assume he was randomly teleported and survived because he never appeared again after CA but there's no hint that the Tesseract can have some kind of negative feedback over the users... Although we all know that the all the Stones can kill their users if they aren't strong enough, so, yeah, there's still the possibility it has desintegrated him