Board Thread:Fun and Games/@comment-25322628-20160912191347/@comment-25322628-20161007040246

Which is why I say only potential inevitability. Since we don't know if the Ego Gem/Stone will even be included in the MCU. Who knows for sure, maybe it's a potential subplot in the works.

Six is just the standard number of stones/gems. If Thanos of the MCU has never had all the stones once before, then it could be an extra requirement just to be able to use the other stones in tandem.

Fool had the Mind Stone, and he foolishly gave it to Loki, who lost it to the Avengers, and they used it to make Vision.

If it had been me, I would've just used the Stone to just control Loki because he can't be trusted, no matter what he does.