New York Sanctum

The New York Sanctum is one of the three bases of the Masters of the Mystic Arts alongside the London Sanctum and the Hong Kong Sanctum. Located in New York City, it is used to store and secure mystic items such as the Dark Scepter and the Cloak of Levitation. The current master of the Sanctum is Wong, after Doctor Strange became a casualty in the Infinity War.

Retrieving the Dark Scepter
The Masters of the Mystic Arts defeated the Witch in London; Wong and Daniel Drumm took the Dark Scepter she once possessed to be safeguarded at the New York Sanctum.

Battle at the New York Sanctum
"Well, a powerful sorcerer, who gave himself over to an ancient entity who can bend the very laws of physics, tried very hard to kill me, but I left him chained up in Greenwich Village, and the quickest way back there is through a dimensional gateway that I opened up in the mop closet."

- Doctor Strange As the Zealots attacked the London Sanctum, Stephen Strange was thrown into the Sanctum through its portal on Kamar-Taj. He witnessed the Zealots killing Drumm before taking them on. During the fight, Strange used the Rotunda of Gateways to trap the Zealots across Earth. As Strange and Kaecilius fought, one of the relics stored there, the Cloak of Levitation, was released and started to defend Strange. Strange immobilized the Zealot leader Kaecilius with the Crimson Bands of Cyttorak and, as he talked to him, he was attacked and stabbed by Lucian with a Space Shard. As the Cloak pinned the Zealot behind, Strange created a portal to Metro-General Hospital seeking the help of Christine Palmer.

Battle of the Mirror Dimension
Once Strange returned, he found Karl Mordo and the Ancient One assessing the damages, with Kaecilius already gone. The Ancient One invited Strange to become the new Master to replace the now deceased Daniel Drumm, but he refused the offer. Later, Kaecilius and the Zealots returned to the Sanctum and prepared to destroy the New York Sanctum. Mordo leapt to fight the Zealots but, before they could destroy the building, Strange dragged them all into the Mirror Dimension to isolate them from the Physical World. Kaecilius began manipulating the Mirror Dimension and gave chase to Strange and Mordo outside the Sanctum and throughout New York City.

After Doctor Strange had defeated Kaecilius and the Zealots in Hong Kong, Strange accepted his duty and moved into the New York Sanctum.

Meeting with Thor
Months into his time as the New York Sanctum's guardian, Doctor Strange kidnapped Loki and invited Thor into the New York Sanctum. There, Thor was warmly greeted with tea, which was then transmutated into beer in his hand. Dr. Strange agreed to release Loki and help Thor search for his father, Odin, who had been exiled to Earth, on the condition that all parties return promptly to Asgard thereafter. Thor was abruptly teleported around the Sanctum with Dr. Strange while discussing this, with Thor breaking a bookshelf at one point.

Doctor Strange plucked a hair from Thor's scalp, scanning it with his magic to conjure a portal to Norway, where Odin was. Strange returned Loki to Earth in the Sanctum's atrium, enraging Loki with his supreme sorcery. Doctor Strange whisked the Asgardians away before Loki could attack him.

Trivia

 * "Sanctum sanctorum" is a Latin translation of the biblical term "Holy of Holies".
 * The Sanctum Sanctorum is one of various landmarks featured in the non-canon video game The Incredible Hulk.