Attack on Jeffrey Mace

"The assassination attempt, this crash... It's not a coincidence." "No. Whoever came after us anticipated the protocols, knew we'd fly to safety. The sniper was just their first move. Sabotaging the Quinjet was plan B."

- Jeffrey Mace and Phil Coulson

The Attack on Jeffrey Mace was an assassination attempt on S.H.I.E.L.D. Director Jeffrey Mace made by ex-HYDRA operatives hired by the Watchdogs.

Raid of the Fridge
During the HYDRA Uprising following the Battle at the Hub and the Battle at the Triskelion, Yuri Zaikin was among those who was believed to have been killed on the Fridge when it was attacked by John Garrett, Grant Ward and multiple HYDRA operatives who were sleeper agents within S.H.I.E.L.D. in 2014. However, Zaikin survived.

Project Patriot
"The president tasked me with finding the next Captain America. Not an easy job, But I did it! I delivered a Patriot, a bona fide American hero!"

- Glenn Talbot

After S.H.I.E.L.D. was legitmitized following the Destruction of HYDRA and the death of Hive, Jeffrey Mace was appointed the new S.H.I.E.L.D. Director after he had saved many lives following the Bombing of the Vienna International Centre. It was made clear that the new Director had to be Inhuman, and since none of the candidates fit the criteria (neither did Mace), Glenn Talbot injected Mace with the Patriot Serum as part of Project Patriot, which had imbued him with superhuman strength that would have made it seem as if he was Inhuman. The serum was kept near Mace in a biometric briefcase, carried by Burrows, a public relations S.H.I.E.L.D. agent and a right-hand to Mace.